Welcome to the Home Page of Stack-ORI

We employed 12 feature encoding schemes that cover nucleic acid composition, position-specific, and physicochemical properties information, whose corresponding optimal feature set identified and developed their respective baseline models using eXtreme Gradient Boosting (XGBoost) classifier. Subsequently, the predicted scores of 12 baseline models are integrated as a novel feature vector to train XGBoost and develop the final model. For a given sequence, Stack-ORI predicts its calss and probability values

Paste or upload Droshophila Mealnogaster Kc cell DNA sequence below (The input FASTA sequences should be 300 base pairs)




File:



Sample FASTA sequences

>P1
GTACCGTTCTGGGTAGAGATAATTTTTTATTTTTTCTTTACTTCTTTGGAGGACCCCGACATTCAACTCCTTACACCCCTTTTCCTTCTCCGTCTATACAGGAACGTCTTCCCAGTTCCCTAGTCTTACCCGAGGAGGGTGAACGAGGGGAGTAATTTTCGGACCAAATAAAAAGAGAAAGAACAGGACAGGTCCGAGTGTCTTCGGTTGGGGTCTCCCGGCTCTCAGGTCGGCCTTCCAAGGAGGCGTCTTCGGGTCCGCTTCGGGATTGTGGGTCGAGAGACAGAGGAAGCTACTCAG
>P2
ACACCGACCGGAAGACTACCTCGGGTGAGTACGACCCGGCGACGGGTCCCCGAAACACCGTGGATCCAGCTCTACCATGAGTCCGGTCCCCAGTCCTAAGGACCCACGAGACCAGGGCCACGGAGACAGAGTAGAAATCCGACCCTAAGGACGGTGGAACGACGAGACCCCGGGTTTATGAAACTCTGTTCCGATATCCGAACAGGGTGACTGAGAGGAAAGGGAGGGACCCCAGAGGAGAGAGAGGTCTCTACGGGACATAGGTTCGGGTTATACCCTGTGGTCGTGGCTCAGGCCCTG
>P3
CTGGTCTCGAACTCCTAGGCTTAAGCGTCCTCCCACCTTGGCCTCCCAAAATGTTGGGATTATAGGTGTGAGCCATGGCGCCCAGCTTGGAATGATGTGCTTGAGCCTGAGGGTGGGGGTGGGCTAGTGTGGAGTGGAGAGGCAGCTTAGGTGGCAGCTGGAACAGATCCTCTGAGGATTGTGGGAGGAGGCCAAAGGCAGATGTGCTGGTGGGGGCTGAGGAAAAAAGACAAGGTCATCAGCTGGGGGTAGGAGCAAGATGGGTAGGGGAGAGGGGAGGGTGCCCAGGCCAGGGGAGTG
>N1
AATCATCCTAACAAGCCGACAACATATCTATGGGCCTAAAAAACTTAAATTCTTTCCCGTTATTAGCACTTCTCGATCGTTCCAGGAAAGCCCGATTTGTAGCTTGGCTGCCCCAGGAAGGGGCCTGCGACCAGAAAGATGCAAAGGGCGGGACAAGGTTACGAGTGGGTGCGGGGAAGCCTCCCTAACCTGGGGGCCGCGTCCCAGAGCTGCGAGCCACGCCTCCTCTCTCCCGCCCGCCGCGCCGCCGGACTCTTATTTTGAAGGGCGGCGGGTGAAGGCTCGGAGCCTCCTGAGTCA
>N2
CCACGACACACGGCTCCTCTCAGCAGGAGTCCTTCCCAGCAAAGGCTCCCCCAACACACCCCGTTCCACATCACGGAGTGCCAGCCCCGGCCCAGCCCGGCTCATCCTCAGGGAGATGGACTCAGCAGGGCTGCCAGAGCCCAGGCCAGCGCTGCTCCCTCCCTCACCGTCCACAACCAGGGCCAACTCATCTTCACAGCTCGACCCCATGCTCTGGTCACTTTTCAGCCCAGTGACTGTTTCAAAGGCATCTGGCACAAGTCAGGAGAGTGCTGTGGAGTCAGTGGAGGCTCCCAGCCA
>N3
ACACCGACCGGAAGACTACCTCGGGTGAGTACGACCCGGCGACGGGTCCCCGAAACACCGTGGATCCAGCTCTACCATGAGTCCGGTCCCCAGTCCTAAGGACCCACGAGACCAGGGCCACGGAGACAGAGTAGAAATCCGACCCTAAGGACGGTGGAACGACGAGACCCCGGGTTTATGAAACTCTGTTCCGATATCCGAACAGGGTGACTGAGAGGAAAGGGAGGGACCCCAGAGGAGAGAGAGGTCTCTACGGGACATAGGTTCGGGTTATACCCTGTGGTCGTGGCTCAGGCCCTG




Reference

Computational prediction and interpretation of cell-specific replication origin sites from multiple eukaryotes by exploiting stacking framework (Submitted).  
[Please cite this paper if you find Stack-ORI is useful in your research] 

Contact: bala@kias.re.kr